AACC 2009: Tosoh Advancements in HPLC and Immunoassay Testing

May 19, 2009 …  At AACC 2009 Annual Meeting in Chicago, IL, Tosoh Bioscience (Booth #3140) will feature advancements in HPLC and immunoassay testing.  Events from Tosoh Bioscience include free educational seminars by David Plaut on the booth stage.  Plaut’s annual AACC educational seminars are eagerly anticipated as a source of pertinent information from immunoassay and HPLC testing.  Also, David provides immunoassay and HPLC case studies for reference.  David Plaut will give free CDs of his seminar information to attendees.
 

AACC 2009 PRODUCT SHOWCASES

There will also be excitement revolving around the Tosoh product line at AACC 2009, as Tosoh will be introducing a new analyzer for immunoassay testing: the AIA-2000 Automated Immunoassay Analyzer.  With a throughput of 200 tests per hour, the AIA-2000 provides all the speed and flexibility necessary to excel in high throughput laboratory testing environments.  Expanded functionality has been added to the system, improving laboratory workflow and increasing walk away time.

Advancements in HPLC and Immunoassay Testing from Tosoh
AACC 2009 Tosoh HPLC and Immunoassay Testing

Advancements in HPLC and Immunoassay Testing from Tosoh

Also for Immunoassay testing, the AIA-360 is a sophisticated system that fits in any lab environment.  With a footprint of 16 X 16 X 21 inches and weighing approximately 60 lbs., the AIA-360’s compact design makes it ideal for physician office laboratories, work stations for small hospitals, STAT testing, such as cardiac panels, as well as a dedicated system for specialty testing.  With a throughput of 36 tests per hour, the AIA-360 generates its first result in approximately 20 minutes.  The cost effective system utilizes the same 10 minute ST reagents as Tosoh’s larger systems, making it the perfect back-up analyzer.

Tosoh’s AIA-600 II is a proven system and has earned the industry-wide reputation of high reliability for immunoassay testing.  The analyzer provides big system features in a bench top analyzer.  Fitting in just 30 inches of counter space, the AIA-600 II has a throughput of 60 results per hour including STAT assay results in ~18 minutes, making it an ideal solution for time-critical tests such as cardiac markers. 

All Tosoh AIA immunoassay testing systems utilize the same Unit Dose Test Cup reagent format, ensuring consistent performance every time.  With interchangeable reagents on all Tosoh systems, inventory management is easy and problem free.  Transition from one system to another is seamless, ensuring consistent results and efficient, economical operation for the laboratory.

For HbA1c testing, Tosoh’s G8 HPLC Analyzer provides one of the industry’s lowest CVs of less than 2%. The NGSP certified instrument-reagent system utilizes the gold standard ion-exchange method for HbA1c testing to effectively monitor glycohemoglobin in diabetic patients. With a compact footprint of 21?w x 19?h x 20?d, the G8 fits easily in most laboratory environments. The G8 provides fast results with an HbA1c analysis time of only 1.6 minutes. Simple touch-screen operation, as well as automatic start-up and daily maintenance make the system extremely user-friendly. 

The Tosoh G7 HPLC Analyzer can be used for both HbA1c and beta-thalassemia testing in one compact analyzer.  The system provides beta-thalassemia results in less than 8 minutes with quantification of HbF and HbA2.  Also, the NGSP certified G7 HPLC Analyzer delivers presumptive identification of HbS, C and D; as well as true separation of Labile and Stable A1c.

With the TRCRapid-160 (Research Use Only), Tosoh has responded to the growing need and acceptance of molecular diagnostic devices.  This accurate and full-featured platform delivers accelerated real-time RNA amplification and detection by combining two innovative technologies - the isothermal TRC reaction and the unique INAF fluorescence probe.  This technology features much lower reaction times than seen with traditional real-time PCR.  This instrument has the potential to be used in many testing areas, such as infectious diseases, cancer markers and environmental testing.

In 2009, Tosoh Bioscience, Inc. is celebrating 20 years in the diagnostic industry.  Started in 1989 as Tosoh Medics, Inc., the company is committed to providing quality diagnostic systems and priority service to laboratory customers.  TBI has sustained double digit growth over the past 8 years, surpassing the industry growth of ~ 4%, with 2008 being the most successful year to date.   Sales of Tosoh Bioscience analyzers and assays have grown consistently throughout the years.

Tosoh Bioscience 
AACC Booth #3140

AIA 600 II Training Videos Available on Web | Video Script

(April 26, 2009) … Training Videos for the AIA-600 II Automated Immunoassay Analyzer are now available for viewing at IMMUNOASSAY TESTING.COM

AIA 600 II TRAINING VIDEO SCRIPT

Written by Bill Bevington, Technical Trainer

Reagents

There are three common reagents used on the 600 II. All assays use the same wash, diluent, and substrate. Sample diluting solutions, calibration/verification material, and calibrators are specific for each analyte. Refer to the analyte application manual for information about any of our reagents.

Substrate II is packaged with 2 sets per box. Each set consists of one bottle of lyophilized substrate and one 100 ml bottle of reconstituant. Add the entire contents of the bottle of reconstituant to the bottle of substrate. Once it has dissolved it is ready to use.

Once the substrate has been reconstituted it should be protected from light. It is stable for 3 days if kept at room temperature and 7 days if kept in the refrigerator after use. Do not mix one bottle of substrate with another. Do not add new substrate to substrate that is about to expire. Label with the date you reconstitute it so you will know when it will expire. Read more »

Beta Thalassemia Testing Video: Tosoh G7 HPLC Analyzer Beta Thalassemia Test Mode

April 10, 2009 - Beta thalassemia testing video describes process of switching to Beta thalassemia test mode on G7 HPLC Analyzer.The Tosoh G7 Automated HPLC Analyzer has both hemoglobin A1c and Beta-thalassemia programs to provide full patient profile. The Beta-thalassemia program quantifies hemoglobins F and A2, which are used in screening for Beta-thalassemia. In addition, the Beta-thalassemia program is used for presumptive identification of hemoglobins S, C and D and for screening for other hemoglobinopathies.

HPLC is the preferred methodology for hemoglobinopathy screening and since the G7 can be used for both hemoglobin A1c and Beta-thalassemia testing, it is 2 instruments in 1! The G7 provides time and labor-savings with primary tube sampling, automated cap piercing and positive sample identification. Most importantly, with less than 2% CVs the G7 offers a high level of both precision and accuracy, and is NGSP-certified.

Switching between the hemoglobin A1c and Beta-thalassemia programs is very easy, simple and fast. Just remove the hemoglobin A1c reagents, replace them with the Beta-thalassemia reagents, and let the instrument do the rest. Once the buffers and column have been changed, the system is automatically primed and is ready to perform analysis within minutes.

HPLC News: Tosoh G8 HPLC Analyzer

Tosoh G8 HPLC Analyzer
High performance liquid chromatography (HPLC) is the gold standard methodology for the HbA1c test. By manipulating the flow rate of the liquid (i.e. mobile phase) and the temperature of the HPLC column (i.e. stationary phase), it is possible to change the chromatographic display.

Early theories on chemical compounds were determined using simple methods (i.e. LC-MS and reverse-phase) and reagents (i.e. acetic acid and acetonitrile). However, since its humble beginning in research, HPLC is now widely used for diagnostics as the main technology in hospital departments. Furthermore, due to the numerous improvements in the performance of the columns and solvents, the chromatographic quality has become so accurate that a gradient can be used for customized elution patterns. Read more »

Diabetes Monitoring: Blood Glucose Monitoring And HbA1c Testing

A diabetes educator needs to inform the patient about proper diabetes monitoring and management tools.  This includes daily monitoring of glucose levels via a glucose meter.  In addition, monitoring diabetes at regular check-ups with their physician, using the Hemoglobin HbA1c test, is recommended.  A variety of diagnostic systems are available for HbA1c testing, including the recently FDA cleared G8 HPLC Analyzer from Tosoh Bioscience.

Resources devoted to helping diabetics include information about diabetes management using glucose meters for self-monitoring of blood glucose (SMBG).  These meters enable patients to monitor and  maintain a more constant blood sugar level. In addition, some patients require continuous glucose monitoring systems (CGMS). Urine is often tested on patients with diabetes to check for diabetes-related kidney disease and severe hyperglycemia. Finally, patients should contact their healthcare provider to determine which option is best for them. Read more »

Tosoh G8 Cleared by FDA

VIDEO: G8 HPLC Analyzer Provides Low CVs for Precise HbA1c Testing

Educational Seminar: PTH at AACC

VIDEO: David Plaut on PTH | Educational Seminar at AACC

PTH on the AIA-360

VIDEO: David Plaut and Bill McLellan discuss PTH on the AIA-360 at AACC

HbA1c at AACC

VIDEO: David Plaut and Bill McLellan discuss HbA1c Testing at AACC 2008

Molecular Diagnostics at AACC 2008

VIDEO: David Plaut and Bill McLellan discuss molecular diagnostics at AACC 2008.